Lāʻau Lāpaʻau || Artichoke Leaf Extract Improves Liver Disease Parameters in Patients with Non-alcoholic Fatty Liver Disease

Crooked Bear Creek Organic Herbs

Non-alcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, is associated with metabolic syndrome. It can progress to cirrhosis and hepatocellular carcinoma; however, the progression is potentially reversible. The few therapeutic agents approved to treat the disease are not always successful. Some studies suggest that for people with the disease, dietary modifications of macronutrients and micronutrients and the use of phytochemicals can be beneficial. Artichoke (Cynara cardunculus Scolymus Group, Asteraceae) leaf extract (ALE) has shown potential as a lipid-lowering and hepatoprotective agent because of its component antioxidants, sesquiterpenes, and flavonoids.

These authors previously conducted a systematic review and meta-analysis of the literature on the lipid-lowering effects of artichoke extracts.They concluded that in patients with mild-to-moderate hypercholesterolemia, the consumption of artichoke extract significantly reduced total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides but did not affect high-density lipoprotein cholesterol (HDL-C). The effects appeared to…

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