Lāʻau Lāpaʻau | Clinical Trial Finds that Walnut Leaf Extract is Ineffective for Reducing Cardiovascular Risk Factors Associated with Type 2 Diabetes

Crooked Bear Creek Organic Herbs

Walnut (Juglans regia, Juglandaceae) is a large deciduous tree native to Central Asia. It has been in cultivation across the Eurasian continent for thousands of years. While it is primarily grown for its exceptionally nutritious nut, it is also a source of dye, wood, and other products. In this double-blind, placebo-controlled, parallel group, clinical trial, the researchers evaluated the effects of a walnut leaf extract on glycemic control and cardiovascular risk factors in patients with type 2 diabetes.

Walnut leaves for this study were collected in the Dasht-e Naz agricultural area outside the city of Sari, Iran. They were positively identified and certified by a botanist, and a botanical quality voucher specimen was deposited at the Sari School of Pharmacy. The walnut leaf sample was air-dried at room temperature. One kilogram of the sample was ground and percolated, using three 2.5 L measures of 70% ethanol over 24…

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